OPEN Research Support
head

MD, Ph.D.
Mads Hjortdal Grønhøj
Department of Neurosurgery, Odense University Hospital


Projekt styring
Projekt status    Open
 
Data indsamlingsdatoer
Start 15.09.2023  
Slut 30.11.2023  
 



IONM versus no IONM during surgical resection of contrast enhancing motor eloquent tumors - two comparable prospective observational cohorts

Short summary

Quality of life is reduced in patient suffering neurological deficits after brain surgery, however, it must be counterbalanced with insufficient resection and thus early tumor progression. Up to now there is no high evidence trial reported in literature, which analysed the benefit of the intraoperative use of neuromonitoring (IONM). We therefore set out to compare motor-deficits in patients with motor-eloquent tumors having surgery with IONM, vs patients having surgery without IONM.


Rationale

We hypothesize that the use of IONM is associated with a higher extent of tumor resection and better neurological outcome at day 1 and day 30 post-surgery.


Description of the cohort

Patients from the Region of Southern Denmark with contrast enhancing lesion on MRI (high grade tumors and metastasis).


Data and biological material

Data from patient journal (diagnosis, gender, age, comorbidity, medication, scans, GCS, performance status) and results from neurological test (Muscle power assessment scale (MRC), NIHSS, 9-hole peg test, 10 meter walk test, Gripstrength, Six spot step test, Engel classification)