Assesment of tensile strenght and histological features of cerebral aneurysms.

MD, PhD
Troels Halfeld Nielsen
Department of Neurosurgery

Projekt styring

Projekt status	Open



Data indsamlingsdatoer
Start	01.01.2017
Slut	01.01.2025

Projektet i tal

OPEN undersøgelse/kliniske data
Forventet # af deltagere	100
Inkluderet antal deltagere	72



OPEN Biobank
Forventede deltagere med prøver	100
Inkluderede deltagere med prøver
Prøver

Assesment of tensile strenght and histological features of cerebral aneurysms.

Short summary

It is still unknown why some cerebral aneurysms rupture, while the majority don't. The present project aims at assessing histological features and wall tensile strengh in both ruptured and unruptured aneurysms. We will explore the differences between the two kinds of aneurysms.

Description of the cohort

Patients are prospectively included the the departments of Neurosurgery at Rigshospitalet and Odense University Hospital

Data and biological material

Aneurysm wall from both ruptured and unruptured cerebral aneurysms are harvested during microsurgical clipping. The tissue are examined in respect to wall tensile strengh, histological features and proteomics.

Collaborating researchers and departments

Department of Neurosurgery, Rigshospitalet