PhD-student
Ann Sophia Bertelsen
1Department of Geriatric Medicine, Odense University Hospital, Svendborg Hospital; Department of Clinical Research, University of Southern Denmark
| Projekt styring | ||
| Projekt status | Open | |
| Data indsamlingsdatoer | ||
| Start | 01.08.2022 | |
| Slut | 31.07.2025 | |
"ROBot assisted physical training of older patients during acUte hospitaliSaTion - a randomised controlled trial (ROBUST)"
Short summary
Inactivity during hospitalisation is associated with significant risk of functional decline especially in older patients. This study aims to address if robot assisted physical training can prevent functional decline during acute hospitalisation in older geriatric patients. The primary outcome, functional decline, will be assessed by Barthel-Index and 30s chair stand test.
Rationale
Inactivity during hospitalisation is associated with significant risk of functional decline especially in older patients. This have major impact on the individual level due to decreased wellbeing and higher level of dependency and on the society level due to increased caregiver burden following hospital discharge.
If our study find that the use of a training robot improves the functional capacity of older people following hospitalisation this will have major impact for the individual patient due to increased wellbeing and higher level of independency. In addition, the society will benefit due to potentially decrease in caregiver burden in the municipality following discharge from hospital. It is expected that the majority of all older people, who are admitted to medical wards, will be able to benefit from the training robot and thus achieve the positive gains from this training. Thus, the study is expected to help change clinical practice for optimal rehabilitation of older persons.
Description of the cohort
ROBUST is a blinded RCT. Patients (n = 488) admitted with acute medical illness to Department of Geriatric Medicine, Odense University Hospital will be randomised to usual care and robot assisted active strength training twice daily (intervention group) or usual care and robot assisted passive sham training (control group) until discharge. Both groups will receive protein supplements Inclusion criteria: ≥65 years of age, able to ambulate before hospitalisation, expected length of stay ≥2 days. Exclusion criteria: Able to ambulate without assistance during current hospitalisation, severe dementia, delirium, conditions contradicting robot training.
Data and biological material
The primary outcome, functional decline, will be assessed by Barthel-Index and 30s chair stand test. Secondary outcomes include Quality of life (EQ-5D), Geriatric Depression Scale, Fear of falling (FES-I), cognition (MMSE), qualitative interviews, falls, caregiver burden, discharge destination, readmissions, healthcare costs, sarcopenia, and mortality. Outcomes will be assessed at admission, discharge, and one- and three months follow-up. Data on comorbidity, medications, blood samples, and clinical frailty scale will be collected.