Master of Science in Midwifery
Anne-Line Brülle
Department of Gynaecology and Obstetrics
| Projekt styring | ||
| Projekt status | Open | |
| Data indsamlingsdatoer | ||
| Start | 12.12.2022 | |
| Slut | 01.02.2024 | |
Ambient air pollution and time to pregnancy - a study within the Danish National Birth Cohort
Short summary
The influence of exposure to air pollutants on couple-fecundity is not yet well established. We will estimate fecundability ratios according to levels of air pollutants in quartiles by discrete time survival analysis with 95% confidence intervals and infertility (TTP>12 months or use of infertility treatment) odds ratios by multivariable logistic regression. We will adjust for several potential confounders chosen a priori.
Rationale
Air pollutants are suggested to have adverse impacts on human reproduction, but the influence of exposure to air pollutants on couple-fecundity is not yet well established. We will investigate the relationship between 10 air pollutants and their association with time to pregnancy (TTP) and infertility in pregnant women from the Danish National Birth Cohort recruited 1996-2002.
Description of the cohort
Women with planned or partly planned pregnancies ending with a live born infant enrolled in the Danish National Birth Cohort 1996-2002.
Data and biological material
Self-reported time-to-pregnancy, use of infertility treatment, socioeconomic status, smoking habits, pre-pregnancy weight and height, parity, level of airpollutants on residential address.