Sofie Dahl-Nielsen
Gitte Zachariassen
HC Andersen Children's Hospital, OUH and SDU
| Projekt styring | ||
| Projekt status | Open | |
| Data indsamlingsdatoer | ||
| Start | 16.07.2023 | |
| Slut | 31.05.2025 | |
Milk Fat Globule Membrane (MFGM) and Extracellular Vesicles (EV) in preterm and term human milk
Short summary
Both MFGMs and EVs serve important nutritional and bioactive purpose for the developing infant. Infant term formulas supplemented with polar lipids from MFGM and EVs show well documented health benefits in term infants, including improved neuro- and cognitive development, less incidences of diarrhea, protective immunological and metabolic effects. We hypothesize preterm infants also will benefit from MFGM and EV added to donor human milk or pretem formula.
Rationale
The present study aims to determine the amount of MFGM and EVs in preterm milk with the perspective to assess how much MFGM/EV should be added to improve the nutrition for preterm infants.
Description of the cohort
30 women who delivered a preterm born infant (before GA 35 weeks) 30 women who delivered a term born infant (after GA 36 weeks)
Data and biological material
Human milk samples and • GA at delivery • Birthweight of the infant(s) in gram • Smoking (how many each day) • Delivery method (vaginal/caesarian section) • Pre pregnancy BMI • Child number • Gender • Single or twin/multiple birth
Collaborating researchers and departments
SDU, ARLA Food Ingredients, Aarhus University