M.D.
Kristian Bach Laursen
Deparment of Cardiology B, Odense University Hospital
| Projekt styring | ||
| Projekt status | Open | |
| Data indsamlingsdatoer | ||
| Start | 01.12.2024 | |
| Slut | 20.12.2028 | |
Diastolic Blood Pressure in Patients with Severe Aortic Stenosis undergoing Transluminal Aortic Valve Replacement
Short summary
Since 2007, cardiologists at Odense University Hospital have treated patients with narrowed aortic valves via the groin. The exact cause of this narrowing is unknown, but it generally results from tiny cracks in the valve's cartilage flaps. These cracks expose the cartilage and cells, triggering a reaction similar to bleeding, leading to scar tissue and calcification. This narrowing forces the heart to work harder, enlarging and damaging the heart muscle. Inserting a new valve reduces resistance
Rationale
Since 2007, cardiologists at Odense University Hospital have treated patients with narrowed aortic valves via the groin. The exact cause is unknown but involves tiny cracks in the valve's cartilage, leading to scar tissue and calcification. This narrowing forces the heart to work harder, enlarging and damaging the heart muscle. Inserting a new valve reduces resistance, raising systolic blood pressure, while diastolic pressure may stay the same or fall.
Description of the cohort
All comers for transluminal aortic valve replacement a the deparment of cardiology in Odense, in the period 01-01-2016 to 31-12-2019.