PhD-student
Emma Illum
Cardiology department, OUH
| Projekt styring | ||
| Projekt status | Open | |
| Data indsamlingsdatoer | ||
| Start | 01.10.2024 | |
| Slut | 01.10.2028 | |
Patient selection and inequality in advanced therapy for cardiogenic shock complicating acute myocardiel infarction - RETROSHOCK Spoke
Short summary
Cardiogenic shock remains a devastating complication of acute myocardial infarction with high mortality. Not all patients gain access to specialized centers offering advanced therapies, and regional as well as socioeconomic disparities may influence treatment pathways. By combining clinical registry data with socioeconomic and geographic information, this project aims to identify patients treated only locally, explore inequalities in access to advanced care and guide strategies to improve equity
Rationale
The purpose of this PhD project is to investigate regional and socioeconomic disparities in the management of acute myocardial infarction and cardiogenic shock. Specifically, it aims to quantify the proportion of patients treated exclusively at local hospitals, examine regional referral patterns, and explore the association between socioeconomic factors and access to specialized care.
Description of the cohort
The cohort will include patients with cardiogenic shock complicating acute myocardial infarction (AMICS) who were admitted to local hospitals (spoke sites) in the Region of Southern Denmark, Region Zealand, and the Capital Region between January 1, 2016, and December 31, 2023. Patients will be identified through the Danish National Patient Registry (DNPR) using a validated screening algorithm. The final cohort will thus consist of patients with verified AMICS who never reached a tertiary center offering advanced therapies, but were instead treated exclusively in local hospitals.
Data and biological material
For each patient, detailed data on demographics, comorbidity, frailty, immediate AMICS management (e.g., vasoactive drugs, mechanical ventilation, renal replacement therapy), and 30-day outcomes will be collected. Linkage with national registries will provide additional information on socioeconomic status, education, income, and geographic distance to specialized centers.