Associate professor, Senior consultant
rajesh prabhakar bhavsar
South jutland hospital Aabenraa, Denmark
| Project management | ||
| Project status | Open | |
| Data collection dates | ||
| Start | 01.02.2021 | |
| End | 31.10.2023 | |
Influence of nociception level monitor (NOL) guided analgesic delivery on perioperative course in breast surgeries.
Short summary
This study explored the impact of nociception level monitoring (NOL) with pectoral (PECS) and parasternal nerve blocks on opioid use and long-term pain after breast cancer surgery. Sixty women were divided into two groups, with one group receiving NOL-guided pain management. Results showed the NOL group used less remifentanil and morphine but had longer periods of inadequate pain. No significant differences in nausea, vomiting, or long-term pain were found, suggesting reduced opioid use .
Rationale
Breast cancer surgeries offer challenges in perioperative pain management especially in the presence of inherent risk for postoperative nausea and vomiting (PONV) and post mastectomy pain syndrome (PMPS). Inappropriate opioid consumption was speculated as one of the reason. This study investigates the impact of objective nociception level monitoring through a nociception level monitor (NOL) combined with pectoral (PECS) and parasternal nerve blocks on intraoperative opioid consumption and long-term PMPS.
Description of the cohort
Female patients (aged 18 to 80 yrs.) with ASA classifications I-III scheduled for elective mastectomy for breast cancer were recruited. Exclusion criteria included inability to consent, atrial fibrillation, local anesthetic allergy, and procedures converted from lumpectomy to mastectomy.
Data and biological material
Patient were contacted 3 months after surgery . They were asked about the nature and severity of pain around the breast insicion.
Collaborating researchers and departments
Department of Anesthesia and intensive care, South jutland hospital, Aabenraa.
Publications associated with the project