Physician/ Senior consultant
Anna Brix /Tine Nymark
Department of Orthopedic Surgery and Traumatology, Odense University Hospital
| Project management | ||
| Project status | Open | |
| Data collection dates | ||
| Start | 01.04.2024 | |
| End | 01.04.2027 | |
Necrotising soft-tissue infections - management and treatment at Odense University Hospital
Short summary
This retrospective, cohort study aims to identify the management and treatment of Necrotizing Faciitis at Odense University hospital. Through patient records, this study investigates the patient flow through departments, the extent of primary secondary and tertiary surgery, the microorganisms found and treatment with antibiotics. Secondary ouctomes are mortality and readmissions. We includes all patients received as a patient with the suspicion of necrotizing faciitis at OUH,
Rationale
The term necrotizing soft-tissue infections (NSTI) covers bacterial infections that lead to deep tissue ischemia and necrosis, often with a rapid onset and severe progression. In Denmark NSTIs are rare (incidence approx. 2/100.000 citizens per year), but severe, with a 30-day mortality at 8-14 %, and 100 % without treatment (1, 2). Overall the treatment is prompt surgical intervention combined with antibiotic treatment and possibly required organ support (3). The diagnosis of NSTI is often first confirmed in the operating room, as no tests can confirm the diagnosis prior to the findings during surgery. Up to 71 % of NSTI is initially misdiagnosed (4). Therefore, it is crucial to always keep the diagnosis in mind and promptly respond to the suspicion of NSTI by scheduling the patient for surgical exploration of the affected tissue. To accommodate the difficulties of prompt initial diagnosis of NSTI, a NSTI-call was made at Odense University Hospital in 2021. Hence this quality project is to aim is to continuously monitor the management and treatment of NSTI patients at Odense University Hospital.
Description of the cohort
All patients ≥18 years who was primary or secondary admitted to Odense University Hospital with or/under suspicion for NSTI.
Data and biological material
Data from reviewing patient records, from 1/1 2020- 1/4 2024