The Impact of Intrapartum Management of Preterm Birth (GA 23-28 Weeks) on Neonatal Outcomes

MD, PhD
Kamilla Karlsen
Department of Obstetrics

Project management

Project status	Open



Data collection dates
Start	01.08.2025
End	01.01.2027

Project in numbers

OPEN survey/clinical data
Expected # of participants	450
Included # of participants





Included participants with specimens
Specimens

The Impact of Intrapartum Management of Preterm Birth (GA 23-28 Weeks) on Neonatal Outcomes

Short summary

The purpose of this study is to examine intrapartum management, including the significance of fetal presentation, fetal monitoring, and mode of delivery among women giving birth extremely preterm (GA 23-28 weeks). Design Prospective data collection, registry-based data. Research Questions Article 1 Descriptive analysis of the birth processes of extremely preterm infants in Denmark. Article 2 Hypothesis: Neonatal outcome at birth between GA 23-28 weeks depends on fetal presentation, fetal monit

Rationale

Extremely preterm birth is rare among singleton pregnancies but carries a high risk of severe consequences for the infant and often leads to prolonged and complicated hospital stays in neonatal units. Intrapartum management of extremely preterm births is characterized by a lack of evidence both nationally and internationally. This applies to the choice of fetal monitoring as well as the assessment of the optimal mode of delivery.

Description of the cohort

Preterm births at gestational age 23-28 weeks during 2022-2024 in Denmark