The effect of intravenous fluids compared to oral fluids on hemodynamics and biochemistry in healthy volunteers

Physician
Peter Biesenbach
Department of Emergency Medicine

Project management

Project status	Open



Data collection dates
Start	16.03.2025
End	30.05.2025

Project in numbers

OPEN survey/clinical data
Expected # of participants	20
Included # of participants



OPEN Biobank
Expected participants with specimens	20
Included participants with specimens
Specimens

The effect of intravenous fluids compared to oral fluids on hemodynamics and biochemistry in healthy volunteers - a randomized crossover trial

Short summary

Randomized controlled crossover study. 20 healthy volunteers will be randomized to receive either 1 liter of Ringer´s Lactate or 1 liter of oral tap water, and crossover afterwards. The primary outcome of the study is the increase in mean arterial pressure (MAP) after 30 minutes compared to baseline.

Rationale

No studies exist comparing the hemodynamic effects of oral and intravenous fluids.

Description of the cohort

Healthy participants

Data and biological material

Blood samples, urine samples

Collaborating researchers and departments

Department of Molecular Medicine

Per Svenningsen