OPEN Research Support
head

Medical doctor
Rasmus Madsen
Department of Anaesthesiology and Intensive Care, Odense University Hospital


Project management
Project status    Open
 
Data collection dates
Start 15.06.2025  
End 31.05.2026  
 



PIEB - Odense 2025

Short summary

A quality assesment of labour epidural analgesia at Odense University Hospital before and after implementation of Programmed Intemittent Epidural Bolus (PIEB). We perform an audit with altogether 200 parturients exploring the incidence of breakthrough pain, pain scores, motor block and ambulation, incidence of adverse effects, local anesthetic consumption and maternal satisfaction.


Rationale

Labour epidural analgesia can be administered as a programmed bolus with a set volume and interval, known as Programmed Intermittent Epidural Bolus (PIEB). It is well-documented that PIEB provides more effective analgesia compared to conventional Continuous Epidural Infusion (CEI). However, PIEB has not yet become a fully established treatment practice in Denmark. This study aims to assess the quality of epidural analgesia in the labour ward at Odense University Hospital before and after implementation of PIEB.


Description of the cohort

Parturients with epidural analgesia in the labour ward at Odense University Hospital. Cervical dilatation < 7 cm at the time of request for analgesia. We perform two separate audits representing 100 women before implementation of PIEB and 100 women after implementation.


Data and biological material

Data is collected using a standardized report form during labour and a satisfaction questionnaire after birth. In addition data will be collected from the patient medical record. Primary Outcome: Number of patients requiring additional epidural boluses (PCEA) Secondary Outcomes: Pain score (Numeric Rating Scale), incidence of motor block (straight-leg raising, Bromage Score), ambulation during labour, incidence of adverse effects (hypotension, urinary retention, nausea, pruritus, hypertermia), maternal overall satisfaction, maternal self-experienced pain score, maternal self-experienced side effects and incidence of delivery mode (vaginal, instrumental, caesarean)