MD Joshua Buron Feinberg Department of medicine, cardiology section, Holbæk Hospital
Projektet i tal
OPEN undersøgelse/kliniske data
Forventet # af deltagere
Inkluderet antal deltagere
Inkluderede deltagere med prøver
Lenient rate control versus strict rate control for atrial fibrillation. The Danish Atrial Fibrillation (DanAF) randomised clinical trial
Randomised trial, comparing a lenient rate control strategy with a strict rate control stategy in patients with permanent atrial fibrillation.
350 participants will be recruited from Holbæk, Hvidovre, Odense and SUH-Roskilde.
Primary outcome is SF-36 physical component score. Primary assessment time point is after 1 year.
Atrial fibrillation is the most common heart arrhythmia with a prevalence of
approximately 2% in the western world and with rising prevalence in the world and
in Denmark. Atrial fibrillation is associated with an increased risk of death and
morbidity and debilitating symptoms such as palpations and shortness of breath.
For many patients, a rate control strategy is recommended over a rhythm control
strategy. The optimal heart rate target is controversial despite the results of the
RACE II trial.
Description of the cohort
Participants with permanent atrial fibrillation recruited from Holbæk, SUH-Roskilde, Odense and Hvidovre Hospital
Data and biological material
blood samples, questionnaire data, data from patient journals, diagnosis, accelerometer data, echocardiography.
Collaborating researchers and departments
Department of cardiology, Odense University hospital
Department of cardiology, Hvidovre University Hospital
Department of cardiology, Zealand University Hospital - Roskilde