NATIONAL REGISTER BASED STUDY ON THE EPIDEMIOLOGY OF TUMOUR INDUCED OSTEOMALACIA (TIO) IN DENMARK
Tumour Induced Osteomalacia (TIO) is a rare, acquired condition of phosphate wasting due to FGF23 secreting, in most cases very small and non malignant, tumours. Surgical cure is possible in patients provided the location of the tumour can be accurately identified by imaging and that the tumour can be reached and removed surgically, or through radiofrequency ablation.
The study is conducted in order to determine the incidence and prevalence of TIO in Denmark over a ten-year period and describe the demographics of this group of patients. This is important because there is a lack of reliable population based estimates on the epidemiology of this disease and the Danish health databases provide a unique opportunity to link relevant databases so that a clear operational definition can be used.