OPEN Research Support
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Læge, Ph.d., Klinisk Lektor
Pernille Just Vinholt
Afdeling for Klinisk Biokemi og Farmakologi, Odense Universitets Hospital


Projekt styring
Projekt status    Closed
 
Data indsamlingsdatoer
Start 01.09.2021  
Slut 01.09.2024  
 



Self-BAT before surgery for prostate, bladder and renal cancer

Short summary

Are the self-administered bleeding assessment tool (self-BAT) useful to identify individuals with increased risk of bleeding during prostate, renal or bladder cancer surgery? For 12 months, self-BAT will be applied to all patients before urogenital cancer surgery. We register self-BAT score, pre-operative laboratory parameters medication and co-morbidity, along with duration of surgery, operative blood loss, transfusion need, 31 day re-operation rate.


Rationale

Blood transfusion during prostate cancer surgery is needed in 0.6-53.3 % of cases and 0.3% need re-operation due to bleeding. Stratifying individuals with increased risk of operative blood loss, transfusion need or re-operation is therefore needed. The international society of thrombosis and hemostasis has developed a BAT to identify individuals with abnormal bleeding tendency, but no studies have evaluated if the self-BAT is useful to identify urogenital cancer patients with increased risk of operative bleeding complications, transfusion need and for planning of surgery.


Description of the cohort

All patients needing surgery for urogenital cancers at the department of urology at Odense University Hospital.


Data and biological material

For the 12 month period, we register age, sex, self-BAT score, pre-operative laboratory parameters (hemoglobin, thrombocytes etc), anti-coagulant treatment, medication and co-morbidity, along with duration of surgery, operative blood loss, transfusion need, 31 day re-operative rate and post-operative laboratory parameters. Additionally, the surgeon will fill out a questionnaire after the procedure to report to which extent the procedure was rated as complicated, whether hemostatic agents (local or systemic) was used, and if knowledge from the self-BAT changed their treatment


Collaborating researchers and departments

Department of urology at Odense University Hospital.