Short summary

Intraperitoneal chemotherapy is increasingly being used in the treatment of peritoneal carcinomatosis in order to optimize local drug delivery and improve clinical outcomes. Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC) is an innovative method of intraperitoneal chemotherapy for peritoneal cancer (peritoneal carcinomatosis), the basic principle of which was first published in 2000.

Rationale

To include data from all PIPAC centers worldwide in a central database in order to monitor treatment quality, perform benchmarking and identify research populations

Description of the cohort

Non-interventional, multicenter data registry for patients treated with PIPAC for malignant peritoneal disease. Patients are included retrospectively and prospectively by the attending physician based on their clinical and histopathological diagnosis of malignant peritoneal disease

Data and biological material

PATIENT:

Registry Patient ID

Date of Birth

Gender

Primary Tumor (incl. "other" site than specified)

Primary Tumor in situ

Primary Histology (incl."other" primary histology than specified)

Known date of diagnose of peritoneal metastasis

Date of diagnose of peritoneal metastasis

Time from primary tumor diagnosis to peritoneal metastasis

Metastasis outside peritoneum

Location of extraperitoneal Metastasis (incl. "other" location than specified)

Previous Oncological Treatment (incl."other" previous treatment than specified)

ECOG Performance Status

TREATMENT:

Type of treatment

Date of treatment

Treatment within prospective Study

Electrostatic Precipitation

Non access

Drug(s)

Oxaliplatin (mg/m2)

Cisplatin (mg/m2)

Doxorubicin (mg/m2)

nab-Paclitaxel (mg/m2)

Flow rate of infusion

Diffusion Time (min)

PCI Score (0-39)

Ascites

Ascites mL

Systemic Chemotherapy within 4 weeks prior to this treatment

RESPONSE EVALUATION:

Date of biopsy

Mean Peritoneal Regression Grading Score (PRGS)

COMPLICATIONS:

Complication / Adverse Event (CTCAE v5.0)

Other Adverse Event

CTCAE Grade

Dindo-Clavien Grade

Date of Complication / Adverse Event

FOLLOW UP:

Last Contact in Institution (Date of latest follow up)

Dead

Date of death