Consultant Nathalie Mella Tejeda Department of Respiratory and Cancer Diseases, Sygehus Sønderjylland
Projektet i tal
OPEN undersøgelse/kliniske data
Forventet # af deltagere
Inkluderet antal deltagere
Inkluderede deltagere med prøver
Two years noninvasive ventilation in chronic hypercapnic COPD.
To evaluate the effect of the addition of nocturnal home NIV to optimal standard treatment among patients with severe stable COPD with hypercapnic CFR.
Many patients with advanced COPD have severe comorbidities which independently impact their prognosis. Therefore, improving survival in hypercapnic COPD patients is challenging. Long term prognosis following hospitalization in COPD is poor, with 5 year motality rates of around 50%.
Therefore, one of the overall goals in the management of COPD is to minimize the number of disease-related hospitalizations, especially in those patients with high risk of developing acute respiratory failure.
Description of the cohort
COPD patients according to standard criteria, requiring invasive or non-invasive mechanical ventilation during an episode of acute respiratory failure due to exacerbation of COPD. Clinically stable and hypercapnic COPD patients.
Data and biological material
Settings and the hours of usage of the ventilator.
Number of exacerbations, hospital admissions, number of in-hospital days, the need for intubation and number of deaths.