OPEN Research Support

Benedicte Schelde-Olesen
Department of Surgery, Odense University Hospital, Svendborg

Projekt styring
Projekt status    Open
Data indsamlingsdatoer
Start 01.09.2020  
Slut 31.08.2025  

Intracorporeal vs. Extracorporeal anastomosis in patients undergoing laparoscopic right hemicolectomy for colonic cancer (ICEA) - A prospective cohort study

Short summary

In this study, we will compare extracorporeal anastomosis (EA) with intracorporeal anastomosis (IA) in patients undergoing elective laparoscopic hemicolectomy for right colon cancer.


At Odense University Hospital, Svendborg, current standard treatment for right colon cancer is laparoscopic hemicolectomy with extracorporeal anastomosis (EA).

To reduce the risk of adverse events, such as fascial dehiscence and later development of incisional hernia, right hemicolectomy with intracorporeal anastomosis has been introduced.

When performing a laparoscopic right hemicolectomy the dissection is carried out intracorporeally and the transection and anastomosis is made extracorporeally (EA technique). For IA technique the cancer bearing segment is resected and the bowel ends joined intracorporeally with laparoscopic technique, and the specimen is then retrieved through a Phannenstiel incision.

Previous series have shown shorter hospital stay as well as shorter time to bowel recovery in patients treated with IA compared to EA, without increasing the risk of severe complications or compromising the oncological outcome.

The aim of this study is to investigate whether IA in patients undergoing right hemicolectomy reduces the overall complication rate compared to EA evaluated by Comprehensive Complication Index (CCI) .

Description of the cohort

Patients over the age of 18 years diagnosed with right colon cancer, eligible for laparoscopic right hemicolectomy with primary anastomosis.

Data and biological material

Data from patient records as well as CT scans and pathological findings will be collected.

Collaborating researchers and departments

Department of Abdominal Surgery, Odense University Hospital, Svendborg

  • MD, PhD Mark Ellebæk