Biochemist, Associate Professor Martin Overgaard Department of Clinical Biochemistry and Pharmacology
Projektet i tal
OPEN undersøgelse/kliniske data
Forventet # af deltagere
Inkluderet antal deltagere
Forventede deltagere med prøver
Inkluderede deltagere med prøver
SugarMum: Screening for gestational diabetes mellitus and abnormal fetal growth
This study investigates how implementation of the new WHO-recommended diagnostic criteria as well as universal screening for gestational diabetes mellitus (GDM) will affect the prevalence of GDM in Denmark. Furthermore, we will explore the potential of multivariate models based on maternal risk factors combined with biomarkers in first and second trimester as alternative screening methods for GDM and large for gestational age (LGA) infants.
Background: In 2013, WHO presented new international recommendations for screening and diagnosis of gestational diabetes mellitus (GDM). Studies indicate that these guidelines are not suitable for all populations, and one study has implied that the prevalence of GDM in Denmark would rise from 4.7 % to more than 40 %, if implementing the WHO threshold for fasting plasma glucose (FPG) alone.
Objective: To clarify the consequences of implementing WHO recommendations for GDM testing in Denmark by comparing the
new WHO method with the current Danish in a prospective study.
Description of the cohort
Prospective cohort of pregnant women attending first trimester screening at Hospital of North Zealand, Hillerød.
Data and biological material
Biobank (serum and plasma) from gestation weeks 11-14 and 24-28.
Data from medical records (maternal characteristics, medication and pregnancy outcome)
Collaborating researchers and departments
Department of Gynecology and Obstetrics, Nordsjællands Hospital, Hillerød
Cathrine Scheuer, PhD student, Tine Dalsgaard Clausen, Consultant, and Associate professor, PhD
Center for Pregnant Women with Diabetes, Rigshospitalet.
Professor Peter Damm
Professor Elisabeth Mathiesen
Steno Diabetes Center Odense/The Research Unit for Gynecology and Obstetrics, OUH.
Professor, Dorte Møller Jensen
Faculty of Medicine, Mater Clinical Unit, The University of Queensland, Australia.