MD, associate professor Dorte Glintborg Department of Endocrinology, Odense University Hospital, Kløvervænget 6, 5000 Odense C, Denmark
Projektet i tal
OPEN undersøgelse/kliniske data
Forventet # af deltagere
Inkluderet antal deltagere
Forventede deltagere med prøver
Inkluderede deltagere med prøver
Feminizing treatment in transgender women and non-binary persons
BIC-estrogen (Body Identity Clinic -estrogen)
The aim of this study is to investigate transgender women and non-binary persons before and during feminizing treatment.
Transgender women are persons assigned male at birth, who identify as women. In transgender women, epidemiological studies reported increased risk of acute myocardial infarction and stroke during feminizing treatment, whereas long-term, prospective studies regarding feminizing treatment and risk of arterial cardiovascular disease are lacking.
The study will focus on:
• Cardiovascular status and lung function
• Body composition
• Mental health and quality of life
• Establish research biobank
The study will bring important knowledge about prospective health in transgender women during feminizing treatment.
If possible, risk factors for adverse physical and mental health during gender affirming hormonal treatment can be investigated.
Description of the cohort
The study includes persons assigned male at birth (+18 years) that either use or want to use estradiol treatment with the purpose of undergoing gender transformation.
Data and biological material
• Medical history
• Physical examination
• Blood and urine samples
• Hair samples
• Computed Tomography (CT) cardiac scan
• VO2 max
• Muscle function tests
• Dual X-ray absorptiometry (whole body, bone)
Collaborating researchers and departments
Department of Endocrinology, Odense University Hospital
Louise Lehmann Christensen
Marianne Skovsager Andersen
Department of Cardiology, Odense University Hospital
Institute of Sports Science and Clinical Biomechanics, University of Southern Denmark
Department of Endocrinology, Ghent University Hospital, Belgium