Short summary

The purpose of this study is to investigate local effects, side effects and quality of life (QOL) in 100 patients who were randomly assigned to rib-oriented (R2 or R2-R3) sympathicotomy for isolated facial blushing at two university hospitals during a 6-year period (2005-2011).

Rationale

Facial blushing is one of the most peculiar of human expressions. The pathophysiology is unclear, and the prevalence is unknown. Thoracoscopic sympathicotomy may cure the symptom and is increasingly used in patients with isolated facial blushing.

During a 6-year period (2005-2011), 100 patients were randomized (web-based, single-blinded) to rib-oriented (R2 or R2-R3) sympathicotomy for isolated facial blushing at two university hospitals. Quality of life (QOL) was investigated preoperatively and after 12 months by Short Form 36. Local effects and side effects were assessed by questionnaire.

1 year after the operation, there were no significant differences in local effects or side effects between R2 and R2-R3 sympathicotomy for isolated facial blushing. Both were effective, and QOL increased significantly. Despite very frequent side effects, the vast majority of patients were satisfied.

Quality of life (QOL) by Short-Form 36, local effects and side effects will now be assessed 10+ years after the operation, through a web-based questionnaire.

Description of the cohort

100 patients randomized (web-based, single-blinded) to rib-oriented (R2 or R2-R3) sympathicotomy for isolated facial blushing at two university hospitals during a 6-year period (2005-2011).