Professor Martin Rudnicki Department of obstetrics and gynecology
Projektet i tal
OPEN undersøgelse/kliniske data
Forventet # af deltagere
Inkluderet antal deltagere
Inkluderede deltagere med prøver
Use of PROdata for evaluation of postoperative pain in women with endometriosis
Endometriosis is an observed in approximately 10% of all fertile women. Hormonal treatment and in some cases surgery is the chosen treatment for relieving pain and improve quality of life in women with endometriosis. Our knowledgde of the natural history of the disease following surgery is limited, but approximately 30% of all women with endometriosis undergoing surgery may undergo repeated surgery.
Endometriosis is a chronic disease and observed in approximately 10% of all fertile women. So far, our knowledge of the natural history of the disease following surgery is limited but approximately 30% of all women with endometriosis undergoing surgery may undergo repeated surgery within three years after primary surgery.
The primary aim of this study is therefore to evaluate if surgery for endometriosis relieves pain and/or recurrence of pain. This will be examined by analyzing PROdata files obtained before and after surgery by women suffering from endometriosis in any stage.
Furthermore, to examine if hormonal treatment reduces post-surgical pain and recurrence of pain in women with endometriosis. This will be evaluated by dividing patients in groups, depending on the hormonal treatment.
The above-mentioned aims will be based on patients who underwent surgery for their endometriosis the last two years including all patients already included in our Prodata base.
Description of the cohort
Patients are identified by ICD10 diagnosis DN 80.9, 80.1-8 and laparoscopy/laparotomy KJAH01 and KJAH00. Cases will be identified from the PROdata database.
Verified endometriosis either by visual identification of endometriosis or pathological examination
Included in the database
Patients not understanding Danish
Patients with mental or similar illness
Patients below age 18
Data and biological material
A sheet (e-CRF) is designed to collect data from medical records. Demographics (age, body mass index) and related medical history (bleeding pattern, parity, uterine length, fibromas or polyps, caesarean section, comorbidities) will be reported. Further the stage (ASRM) and procedures during surgery, place of endometriosis and any resection of tissue, the pathological diagnosis.
All patients have filled in questionnaires which have been stored in the PROdata endobase. The questionnaire includes domains in relation to pain, quality of health, WHO depression scale questionnaire. The PROdata questionnaires have been validated.
We expect <100 women to be included.