MD, PhD, Associate professor, Anne Voss Department of Rheumatology, Odense University Hospital
Projektet i tal
OPEN undersøgelse/kliniske data
Forventet # af deltagere
Inkluderet antal deltagere
Inkluderede deltagere med prøver
ReumaGravid - pregnancies among Danish patients with autoimmune rheumatic diseases.
In the Region of Southern Denmark a cohort of women with autoimmune rheumatic diseases and a wish for pregnancy is established at "Klinik for gravide med reumatologiske sygdomme" in order to describe the course before, during and after pregnancy with special focus on the outcome of the pregnancy and the course of the autoimmune disease.
Pregnancies among women with ARD are more often associated with adverse outcome than pregnancies among women without autoimmune rheumatic diseases.
By an observationel study with prospective collection of data on the mother's disease, the pregnancy and the child, supplemented with up to 5 consecutive bloodsamples per pregnancy, potential risk factors for adverse outcomes are investigated
Description of the cohort
Patients included are adult females with autoimmune rheumatic diseases eg rheumatoid arthritis, systemic lupus erythematosus, Sjögrens syndrome, antiphsopholipid antibody syndrome followed at the "Klinik for gravide med reumatologiske sygdomme" at Department of Rheumatology, OUH.
The woman is included if she plans pregnancy and/or a pregnancy is diagnosed.
The present study is an observational study with prospective collection of clinical data and blood samples.
Visits are planned before pregnancy, a visit in every trimester and a visit 1-4 months after delivery.
Data and biological material
Biobank includes up to 5 consecutive blood samples (serum and plasma) from mother
Data for the study are obtained by interview, clinical examination and scoring of the rheumatic disease, routine biochemical analyzes and by reviewing medical records of mother and child.
Collaborating researchers and departments
Department of Gynecoology and Obstetrics, Odense University Hospital