Professor Niels Qvist Surgical Department A, Odense University Hospital
Projektet i tal
OPEN undersøgelse/kliniske data
Forventet # af deltagere
Inkluderet antal deltagere
Forventede deltagere med prøver
Inkluderede deltagere med prøver
The intestinal innate immune system in newborns. Development and inflammation in health and disease
With this project we want to determine the normal development of the human intestinal immune system in premature and mature neonatal life and to determine the pathophysiology behind life-threatening gastrointestinal diseases that appear during early life. A secondary aim is to investigate the development of the immune system in relation to the enteral nutrition during the neonatal period.
We hypothesize that knowledge gained from our project will improve treatment of infectious and inflammatory diseases of the neonatal gastrointestinal tract, specifically the life- threatening necrotizing enterocolitis (NEC), and challenge current guidelines in enteral nutrition in various diseases and in the healthy child.
Description of the cohort
Premature babies (with or without the development of NEC) and newborns with gastrointestinal malformations
Data and biological material
Fecal samples, intestinal tissue, cinical data in relation to disease/malformation and data on nutritional support.
Collaborating researchers and departments
Department of Neonatology, Rigshospitalet, Copenhagen