Physician
Jan Dominik Kampmann
Internal Medicine Research Unit at Department of Internal Medicine, University Hospital of Southern Denmark, Sønderborg.
| Project management | ||
| Project status | Open | |
| Data collection dates | ||
| Start | 23.08.2023 | |
| End | 01.08.2026 | |
Mortality and Morbidity among patients with Kidney Disease: A Danish nationwide registry study
Short summary
Kidney disease is an important health challenge with up to 10% of the population affected worldwide. Kidney disease is associated with premature death, decreased quality of life and increased risks of morbidity. The objective of this project is to investigate morbidity and mortality among patients with chronic and acute kidney disease. Furthermore, we will investigate risk factors as well as protective factors for developing kidney disease.
Rationale
Kidney disease is an important health challenge with 10% of the population affected worldwide. Kidney disease is associated with premature death, decreased quality of life and increased risks of morbidity. One of the biggest challenges among individuals with chronic kidney disease (CKD), is that large proportions remain undiagnosed. Data from studies indicate that only 9% of patients with CKD are aware of their diagnosis. Early identification of individuals with CKD, followed by the implementation of evidence-based interventions can slow or prevent the progression to advanced stages of the disease and reduce the risk of comorbidity. The risk of comorbidity among patients with kidney disease is high and include both physical and mental health conditions. However, more knowledge is needed on onset of comorbidity vs kidney disease and about interaction between kidney disease and comorbidity. The aim of this project is to add knowledge on prevention, prognosis, and survival of patients with chronic kidney disorders. This includes multiple objectives e.g. to investigate morbidity and mortality among patients with chronic and acute kidney disease; describe and compare patient characteristics among patients followed vs not follow in healthcare and investigate risk factors as well as protective factors for developing kidney disease.
Description of the cohort
We will include individuals over 18 years of age living in Denmark who had blood samples analysed for creatinine in the period from 2014 to 2023.
Data and biological material
Our study will be designed as a national register-based cohort study utilizing several Danish registers, e.g. the National Patient Registry, the Cause of Death Registry, Socio-Economic Registers and Disease Specific Registers.