OPEN Research Support
head

Professor
Christine Stabell Benn
OPEN Odense Patient data Explorative Network, Odense University Hospital


Project management
Project status    Closed
 
Data collection dates
Start 01.01.1996  
End 31.12.2015  
 



Doctor's choice: A study of general practitioner's considerations and contraindications when administering pentavalent vaccine and measles-mumps-rubella vaccine

Short summary

According to the Danish vaccination program, children should receive three doses of pentavalent vaccine (Difteri, Tetanus, Pertussis, Hib, Polio), at 3, 5 and 12 months of age and a dose of MMR (measles-mumps-rubella) vaccine at age 15 months. The vaccines are provided at free consultations with the general practitioner (GP).

Data from the Danish Vaccination Register has shown some variations in administration of DiTeKiPolHib and MMR if the children are delayed at 15 months of age. The study seeks to investigate the extend of the variations, and the underlying cause of these.


Rationale

According to the Danish vaccination program, children should receive three doses of pentavalent vaccine (Difteri, Tetanus, Pertussis, Hib, Polio), at 3, 5 and 12 months of age and a dose of MMR (measles-mumps-rubella) vaccine at age 15 months. The vaccines are provided at free consultations with the general practitioner (GP).

However, based on the Danish vaccine registers there is considerable variation in how Danish children are vaccinated. Around 10% of all children do not get their third pentavalent vaccine before reaching 15 months of age. When coming for vaccination, according to the recommendations these children should receive both the pentavalent vaccine and MMR vaccine provided it is more than 6 months since they got their last pentavalent vaccine. Nonetheless, while some of these children do receive both vaccines, many children receive only pentavalent vaccine, and some receive only MMR. The present project aims to investigate the motives underlying the Danish general practitioner's decisions with respect to pentavalent vaccine and MMR vaccine.


Description of the cohort

Danish children who are delayed in those vaccinations, who should have been administered at 12 months and 15 months of age. 


Data and biological material

Data is collected from the Danish Vaccination Register, in the years 1996-2015. 


Collaborating researchers and departments

Faculty of Health Sciences, University of Southern Denmark

  • Medical student Marie Holck
  • Medical student Kenneth Pedersen

OPEN Odense Patient data Explorative Network, Odense University Hospital

    Bandim Health Project, Statens Serum Institute

    • Professor and senior researcher Christine Benn
    • Statistician Aksel Jensen
    • Senior researcher Signe Sø

    Infectious Disease Epidemiology, Statens Serum Institut

    • Senior researcher Tyra Krause