The goal is to set up a research database for infants suffering from moderate to severe birth asphyxia treated with hypothermia. The data base should contain clinical data from the initial treatment as well as follow up data at 24 months of age. The database should harbor data from all the Nordic countries.
Peripartum asphyxia affects app. 3-5 per 1000 live born infants. From this group 0.5-1 per 1000 live born infants will suffer moderate to severe encephalopathy. Worldwide, 10-60% of infants suffering from HIE will die and at least 25% will survive with neurological deficit. Therapeutic hypothermia for hypoxic ischemic encephalopathy became the standard of care after a series of studies including in excess of 1500 infants which demonstrate a significant reduction in risk of death and severe neurological disability.
This is a very vulnerable group of infants whom we submit to 72 hours of hypothermia. It is important that we still learn from experience hence the need for at database.
Collaborating researchers and departments
Institute of Clinical Medicine, Aalborg University Hospital
- Consultant neonatologist Lars Bendner
Institute of Clinical Medicine, Aarhus University Hospital
- Staff grade Kasper Kyng, PhD
Department of Paediatrics Copenhagen University Hospital, Rigshospitalet
- Consultant Neonatologist Anne-Mette Baek Jensen
Department of Paediatrics Odense University Hospital
- Consultant neonatologist Anne Rikke Ruager
Department of Paediatrics, The Natioanl Hospital, Oslo, Norway
- Consultant Neonatologist Per Arne Tølløfsrud
Department of Clinical Sciences, Karolinska University Hospital, Stockholm, Sweden
- Consultant Neonatologist Boubou Hallberg
Department of Paediatrics, Children's Hospital, University of Helsinki, Finland
- Consultant Neonatologist Metsaranta Marjo
Landspitali University Hospital, Reykavik, Iceland
- Consultant Neonatologist Sveinn Kjartansson