Consultant
Christian Backer Mogensen
Department of Regional Health Research, University of Southern Denmark
Projekt styring | ||
Projekt status | Sampling ongoing | |
Data indsamlingsdatoer | ||
Start | 01.05.2017 | |
Slut | 01.05.2018 | |
Multiresistant bacteria is an increasing problem. Early identification of patients
with multiresistant bacteria is mandatory to avoid transmission and to target the antibiotic treatment. This study will provide a comprehensive overview of prevalence and risk factors for MRSA, ESBL, VRE, CPE and CD colonization in patients admitted to Danish ED`s. It is a multicenter descriptive and analytic cross-sectional survey of around 5000 acutely admitted patients.
Multiresistant bacteria (MRB) is an increasing problem in many parts of the world [1]. In Denmark,
attention has been focused in particular to methicillin resistant Staphylococcus aureus (MRSA), but there has also been an increase in the prevalence of extended-spectrum beta-lactamase-producing enterobacteria (ESBL), vancomycin resistant enterococci (VRE) and carbapenem resistant enterobacteria (CPE). Early identification of patients colonized with resistant bacteria is mandatory to avoid in-hospital transmission and to target the antibiotic treatment to the individual patient.
There is currently very sparse knowledge of both prevalence and risk factors for colonization with MRSA, ESBL, VRE, CPE and CD in acutely admitted patients. The Danish National Board of Health has published guidelines for targeted screening for isolation of MRSA, based on questionnaires concerning exposure factors. This screening is expected to identify only some of the carriers. In order to clarify the extent of the problem and prioritize the preventive response to the spread of MRB, it is crucial to know the prevalence of these bacteria in unselected acutely admitted patients to the Danish EDs.
The aim of this project is to provide a comprehensive overview of prevalence and risk factors for MRSA, ESBL, VRE, CPE and CD colonization in patients admitted to Danish emergency departments at a national level.
The objectives are: I) To describe the prevalence of MRSA, ESBL, VRE, CPE and CD colonization in unselected, acutely admitted patients and the regional, urban / country and other demographic variations. II) To describe the occurrence of simultaneous patient colonization with two or more resistant bacteria (MRSA, ESBL, VRE, CPE and CD). III) To identify risk factors for colonization with MRSA, ESBL, VRE, CPE and CD IV) Based on the identified risk factors, to develop screening tools for identification of carriers.
Acutely admitted adults
Patients will be swabbing in the rectum, nose and throat and will answer a questionnaire.
Department of Emergency Medicine, Hospital of Southern Denmark, Aabenraa and Danish Institute of Regional Health Research, University of Southern Denmark, Aabenraa
Department of Clinical Microbiology, Odense University Hospital
Department of Emergency Medicine, Odense University Hospital and Institute of Clinical Research, University of Southern Denmark
Department of Infectious Diseases, Odense University Hospital
Department of Clinical Microbiology, Hospital of Southern Denmark, Sønderborg
Emergency Department, Regional Hospital West Jutland
Emergency Department, Aarhus University Hospital
Department of Clinical Microbiology, Aarhus University Hospital
Emergency Department, Aalborg University Hospital
Emergency Department, North Denmark Regional Hospital
Department of Clinical Microbiology, Aalborg University Hospital
Emergency Department, Slagelse Hospital
Emergency Department, Zealand University Hospital
Department of Clinical Microbiology, Slagelse Hospital