Professor and consultant David Gaist Department of Neurology, Odense University Hospital
Projektet i tal
OPEN undersøgelse/kliniske data
Forventet # af deltagere
Inkluderet antal deltagere
Inkluderede deltagere med prøver
Women with Migraine with Aura Neuroimaging (WOMAN) study
We collected MRI brain scan and interview data from women with a diagnosis of migraine with aura (cases) and from migraine-free controls. All participants were identified through the population-based Danish Twin Registry. A single 3-Tesla MRI scanner was used for brain imaging. The collected data allow comparisons of brain imaging results of cases with controls (individual-based analyses). For a subset of data, comparisons of cases with their co-twins are also available (within-pair analyses).
Description of the cohort
Women aged 30 to 60 years (n=345).
Cases: women with migraine with aura according to IHS criteria (lifetime diagnosis) (n=172)
Controls: women with no history of migraine of any type, or frequent tension-type headache (n=139)
Co-twins: women with no history of migraine with aura whose twin sister suffered from this headache form; the co-twins could suffer from migraine without aura (n=34).
Data and biological material
Brain MRI imaging results, questionnaire and interview data, blood test results (lipid levels, HgA1C).
Questionnaire and interview data are also available for a larger cohort of women from which we identified participants for the brain imaging study.
Collaborating researchers and departments
Danish Headache Center, Department of Neurology, Rigshospitalet Glostrup
Professor Messoud Ashina
Danish Research Centre for Magnetic Resonance, Copenhagen University Hospital Hvidovre