Short summary

PCOS is defined by irregular menses, hyperandrogenimia and polycystic ovaries. PCOS is associated with increased risk of type 2 diabetes and cardiovascular disease. 

Women are screened metabolically by time of PCOS diagnosis, whereas guidelines differ regarding screening for metabolic risk during follup up. 

The present study will include 200 women with PCOS. The women are evaluated by study inclusion and after 5, 10, 15, and 20 years.   

Rationale

PCOS is defined by irregular menses, hyperandrogenimia and polycystic ovaries. PCOS is associated with increased risk of type 2 diabetes and cardiovascular disease. 

Women are screened metabolically by time of PCOS diagnosis, whereas guidelines differ regarding screening for metabolic risk during follup up. Risk of cardiometabolic disease could be predicted by baseline phenotype.   

The aim of the present study is to follow 200 women with PCOS prospectively regarding cardiometabolic risk factors. 

Description of the cohort

200 women with PCOS. 

Data and biological material

Blood, urine, questionnaires, whole body dxa scans 

Collaborating researchers and departments

Department of Endocrinology, Odense University Hospital 

• Consultant, Dorte Glintborg, PhD, DmSci
• Professor, Marianne Andersen, PhD, DmSci
• Consultant, Pernille Hermann, PhD

Department of Gynechology and Obstetrics

• Consultant, Pernille Ravn, DmSci

Fertility Clinic, Region Sjællands University hospital

• Consultant, Anne Lis Englund, DmSci
• Consultant, Marie Louise Muff Wissing, Phd

Dapartment of Gynechology, Herlev Hospital 

• Consultant, Pernille Svendsen, DmSci

Department of Endocrinology 

• Consultant, Jens Faber, DmSci